PROP | Physicians and Health Professionals for Responsible Opioid Prescribing

Physicians and Health Professionals for Responsible Opioid Prescribing

Opioid Dose Trajectories and Associations With Mortality, Opioid Use Disorder, Continued Opioid Therapy, and Health Plan Disenrollment

In this cohort study, decreasing opioid dose was associated with reduced risk of opioid use disorder and continued opioid therapy but increased risk of disenrollment compared with stable dosing, whereas the high-dose increasing trajectory was associated with an increased risk of mortality and opioid use disorder. These findings can inform opioid management decision-making.

2022_Binswanger_Opioid Dose Trajectories and Associations With Mortality, Opioid Use Disorder, Continued Opioid Therapy, and Health Plan Disenrollment (2)

The fiscal sponsor of PROP is the Steve Rummler HOPE Network, a 501(c)(3) charitable organization. PROP does not accept financial support from pharmaceutical companies and other life sciences corporations.

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